Molecular neuroimaging of oxidative stress in neurodegenerative diseases

Occurring Dates
Participant Duration
3 hours on one occasion
State of study

Are you interested in supporting research into neurodegenerative diseases? Are you aged between 40-65 years old, with no history of neurological illness, major repeated head injury, or severe claustrophobia? You may be eligible to participate in our project at the Harding Lab! The study is being conducted by Dr. Ian Harding, Senior Research Fellow at the Monash University Department of Neuroscience.

Problems with how brain cells produce and use energy, and their ability to get rid of the waste that is naturally created, can have harmful consequences. One of these consequences is known as oxidative stress, which is thought to contribute to neurodegeneration in many brain diseases, including Friedreich ataxia, Huntington’s disease, Parkinson’s disease, Lewy Body Dementia, Alzheimer’s disease, vascular dementia, and Motor Neuron Disease.

This project will use combined Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) brain scanning technology to measure oxidative stress in the brain and determine its relationship with measures of neurodegeneration. This will help determine how critical oxidative stress is to disease expression, and how useful these measures may be, for example, for determining drug effects in clinical trials or determining who may benefit most from a particular treatment.

The research will be undertaken at Monash Biomedical Imaging (770 Blackburn Road, Clayton), and will require up to 2.5 hours of your time, including a 1-hour brain scan. All participants will be reimbursed $50 for their time.

Further information

If you are interested in participating or would like more information, please follow this link to our google form:

Alternatively, you may contact the Harding Lab directly via e-mail at: [email protected] or phone at: 0492 923 663.

We look forward to hearing from you!

The study has been approved by the Monash University Human Research Ethics Committee (MUHREC 2019-18894).

Study Address
Monash Biomedical Imaging
770 Blackburn Road, Clayton, VIC, 3168
Full Name
James Morgan
Monash University
Phone Number
0492 923 663