MK-2214 Drug Trial for people with early Alzheimer's disease
Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease. The goal of the study is to learn if MK-2214 slows the spread of tau in the brain compared to placebo. Tau is a protein that accumulates in AD & damages brain cells.
This study has been approved by a Belberry Human research ethics committee (2025-04-528)
Participation
People who meet the following criteria my be eligible to participate in the study;
- Aged 50 to 85 years
- Have a diagnosis of Mild Cognitive Impairment or Mild Alzheimer's dementia
- Have a study partner who can come onsite for a few hours every 3 months
- No other neurological condition
This trial goes for 2.4 years and involves monthly infusions. Participants will also need to have MRIs, PET scans, blood tests, and cognitive testing.
Participant duration
Monthly participation for 2.4 years
Available to people living in
VIC
Study begins
Wednesday, 1 April 2026
Study ends
Sunday, 1 November 2026
Contact
To find out more about this study, contact:
Laura Margison
Austin Health
mcru.recruitment@austin.org.au
Austin Repatriation Hospital 300 Waterdale Road, Ivanhoe 3079 , VIC
